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Systematic literature reviews
Literature reviews scoped to the decision in front of you.
We define what evidence to find, search the agreed sources, screen the retrieved records against your criteria, and extract the findings into a source-linked synthesis. Our scientists set the criteria and work through screening, extraction, and interpretation, with AI agents doing the repetitive reading.
The scoped review process
From research question to reviewed output.
The review plan, sources, limits, and outputs are agreed for each project. Search and screening decisions remain visible in the review record at the level defined by the scope.
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Define the question and criteria
Agree the research question, populations or concepts of interest, inclusion and exclusion criteria, relevant dates, languages, and other limits.
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Search agreed sources
Search the selected literature and evidence sources. Record the sources, query details, and search dates as defined in the project plan.
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Screen records
Apply the agreed eligibility criteria to retrieved records. Scientists resolve uncertain records and document inclusion and exclusion decisions.
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Extract evidence
Capture the predefined study and finding fields from selected sources, retaining citations so the evidence can be checked.
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Synthesize findings
Compare results, describe areas of agreement and conflict, and identify uncertainty and evidence gaps. Quantitative pooling is only included when separately scoped and supported by the evidence.
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Review and deliver
A scientist reviews the source record, screening and extraction outputs, and interpretation before delivery in the agreed report, evidence table, presentation, or structured format.
Source selection
The source set follows the question.
The selected sources, search period, language limits, and access constraints are defined before work begins. Depending on the question, a review may include biomedical literature, trial registries, journals, or conference records.
What the review can include
A usable record of the evidence.
Outputs depend on the agreed scope and can include a methods summary, search strategy and dates, screened references and exclusions, an extraction table, a source-linked narrative synthesis, and a summary of evidence gaps. The final format may be a report, executive summary, presentation, dashboard, or structured data.
Reviews often feed a target product profile or a competitive landscape. See all solutions.
Scope and limitations
Methods and coverage are explicit.
- Findings reflect the databases, sources, dates, languages, and inclusion criteria agreed for the review; no search can guarantee capture of every relevant or unpublished item.
- Access limits can restrict review of full text. Abstract-only or otherwise incomplete records are identified in the review output when they affect interpretation.
- A literature synthesis does not automatically include a meta-analysis, pooled effect estimate, or formal risk-of-bias assessment; these require separate scope and appropriate data.
- We do not imply that a review is accredited, regulator-approved, or compliant with a formal standard unless that exact requirement is defined and agreed for the review.
Questions and answers
Frequently asked questions.
How is a review scoped?
We begin with the research question, eligible sources, inclusion and exclusion criteria, time period, and other limits that matter to the decision. These are documented in the project plan.
Does every review follow an accredited or regulatory method?
No. Each review is scoped for its question. We do not imply accreditation, regulatory approval, or compliance with a named standard unless that exact requirement is explicitly defined and agreed for the review.
What does the client receive?
Depending on the agreed scope, outputs can include a methods summary, search record, screened references, extraction table, source-linked synthesis, and evidence gaps.
Can the review be updated?
A review can be refreshed when updates are part of the agreed scope. The update scope and cadence are agreed with the client and managed by Epistemic.
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Your next decision starts here
What decision is
your team facing?
Bring us your question. We reply within one business day and help define the analysis that moves you forward.